Indianapolis' central location and extensive highway and rail infrastructure have positioned the city as an important logistics center. According to the Indy Chamber, the region was home to some 4,300 establishments employing nearly 110,000 in 2020.[182]
Amazon has a major presence in the Indianapolis metropolitan area, employing 9,000.[183] Indianapolis is home to FedEx Express's National Hub which employs 7,000 workers in sorting, distribution, and shipping at Indianapolis International Airport.[184][185] Other logistics companies in the region with large workforces include Ingram Micro (1,300) and Venture Logistics (1,150).[185]