Economy Class Syndrome is the medical term for a blood clot(s) in the major veins carrying blood from the lower (usually) limbs to the heart when one may have to sit in the same position for a long time for example, sitting on an airplane for long hours can lead to something called travellers thrombosis, which happens when someone sits in the same position for a long time without much movement and it affects approximately two to three people per 1000 individuals per year. As travelling has opened up, people are continuously flying long hours and travelling several miles to various destinations hence, Deep Vein thrombosis or Economy Class Syndrome occurs to many people when they regularly travel in airplanes and face difficulties related to health and ahead of National Doctors' Day 2022, we are going to throw light on its causes, symptoms and preventive tips.